Mesenchymal stem cells, also known as Mesenchymal Stromal Cells (MSCs), are adult, fibroblast-like multipotent cells that can differentiate and mature into tissues of mesodermal origin such as adipocytes, chondroblasts, and osteoblasts. Mesenchymal stem cells were isolated first time from the bone marrow and later from various sources such as cord cells, adipose tissue, and molar cells. MSCs in terms of size, are smaller and are quite difficult to observe in histological sections. A group of mesenchymal stem cells are called as mesenchyme and is widely distributed in the body. Mesenchymal cells can multiply in numbers of specialized cells and they can grow in-vitro or in-vivo condition.
The mesenchymal stem cells play an important role within an organism for suppression of immune cells activation, increase the number of newer cells, reduce cell death or cell damage in the body, and secretion of both neurotrophic and angiogenic factors, which are responsible for stabilizing the extracellular matrix, when transplanted to the brain, this cells promote the reduction of free radical levels and enhance synaptic connections of damaged neurons, and increases the myelination of axons. The mesenchymal cells are also able to replace and repair any damaged blood vessel in the cerebrum brain.
Rise in prevalence of osteoporosis and increase in cancer incidences are expected to support the global market growth
MSCs have the ability to grow bone tissues through the bone surface to form new bone, which in turn has the potency to treat osteoporosis. According to the National Institute of Health (NIH), in 2015, the U.S. accounted for around 53 million people suffering from osteoporosis or at a high risk due to low bone mass.
According to Osteoporosis Canada, around 1 in 5 men and 1 in 3 women suffer from osteoporotic fracture during their lifetime, whereas osteoporosis causes around 70-90% of 30,000 hip fractures yearly; the annual cost to Canada for treating osteoporosis was around US$ 4.0 billion in the year 2012, which is expected to rise in the upcoming years. Furthermore, according to the International Osteoporosis Foundation (IOF), annually around 9.0 million people worldwide are suffering from osteoporosis fractures. The aforementioned factors are expected to bolster the Mesenchymal stem cells market growth over the forecast period.
North America and Asia Pacific are expected to hold large market shares followed by Europe due to the rapid growth in technological innovations, high disposable incomes, and the well-equipped healthcare centers, which will lead to the growth and development of MSCs market. The implantation of new mesenchymal stem cells in cancer patients is expected to enhance the growth of MSCs market.
Mesenchymal Stem Cells Market Players
Some of the key market players identified across the value chain of mesenchymal stem cells market are, Pluristem Therapeutics, LonzaThermo, Fisher, ATCC, Bio-Techne, MilliporeSigma, Genlantis, Celprogen, Cell Applications, PromoCell GmbH, Cyagen Biosciences, Human Longevity Inc., Axol Bioscience, Cytori Therapeutics, Eutilex Co.Ltd., ID Pharma Co. Ltd., BrainStrom Cell Therapeutics, Cytori Therapeutics Inc., Neovii Biotech, Angel Biotechnology, California Stem Cell Inc., Stemcelltechnologies Inc., and Celgene Corporation Inc.
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