Bone graft substitutes are the materials used for the replacement of the missing bones or gum tissues in the body, It fills the null place of body parts such as knee, wrist, ribs were the bone is absent. The use of bone can be replaced from a donor body or it can be manmade. The common types of bone graft are allograft, xenograft, alloplast and autograft which comes from a bone inside the body, such as hips, pelvis, ribs, or wrist were allograft bone comes from a dead patron that has been cleaned and stored in a tissue bank. Allografts are tissues of the donors of same spices given to the recipient but are not identical were as they are used in knee, hip, or long bone reconstruction dental surgery, and plastic surgery this process is also known as Allotransplantation. Bone graft are synthetic type of a naturally-occurring product Variety of bone graft are available for use in spine fusion surgery, Bone graft substitute is use in lumbar spinal fusion surgery to eliminate the need to yield the patient own bone. Bone graft substitutes are used in spinal fusion surgery, which are categorized into three main areas, Demineralized Bone Matrix (DBM), Bone Morphogenetic Proteins (BMP) and Synthetic bone graft extenders.
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The bone graft substitute is osteoinductive, biocompatible, bioresorbable structurally similar to bone and are easy to use and cost-effective. Bone graft substitute are used in Dental implants, fibular shaft and others. The sources of bone graft are Osteoconduction, Osteogenesis, Osteopromotion, and Osteoinduction. This are the biological mechanisms that provide a basis for bone grafting. The spinal fusion surgery is the most common surgery in this were it is used to correct hitches with the small bones of the vertebrae. Spinal fusion removes motion between vertebrae and it also prevents the stretching of nerves, ligaments and muscles it is an option when motion is the source of pain, such as movement that occurs in a part of the spine were as spinal fusion may relieve symptoms including spinal stenosis, fracture, spondylolisthesis were vertebral compression fractures (VCFs) is the common fracture in patients having osteoporosis.
Increase in spinal fusion, osteoporosis procedures around the globe will be the leading factor for the growth of bone graft substitutes market
The increasing in population and growing prevalence of bone and joint disorders are the main factors boosting the worldwide bone grafts substitutes market. According to National Osteoporosis Foundation (NOF) it is expected the number of cases with osteoporosis will cross 61 million by 2020. Also, as per National Spinal Cord Injury Center in U.S, Researchers have assessed that in 2015, nearly 12500 new spinal cord injury (SCI) occur each year whereas approximately 240,000 and 337,000 people are living presently with SCI. Additionally International Osteoporosis foundation (IOF) estimated that around 50% of all osteoporotic hip fractures will arise in Asia by the year 2050.
Key players for Bone Graft Substitute market includes:
Geistlich North America Inc., Medtronic BioHorizons IPH, ACE Surgical Supply Company, Stryker Corporation, RTI Surgical, Inc. LifeNet Health, Institut Straumann AG, acesurgica supply CO.Inc. DePuySynthes etc.
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