Researchers at King’s College London reported that Cannabidiol (CBD) has potential to reset the brain abnormalities observed in people suffering from psychosis.
Since recent past, compounds such as cannabidiol (CBD) have gained significant traction due to its benefits to neural system without the negative side-effects. New researchers revealed that cannabis extract might help to relieve symptoms of psychosis. Studies reported that neurological and behavioral effects of the cannabis on people are almost the opposite, with evidence suggesting it can calm anxiety and relieve pain. Recently it received FDA approval, as a treatment to reduce seizures in children with a rare form of epilepsy.
As a part of study, researchers examined cannabidiol on a group of young people who were reported to have psychotic symptoms. Out of the 33 test subjects, 16 received a single dose of CBD while the remaining 17 had a placebo and these were compared to a control group of 19 others. After their dose, the participants performed a memory task designed to involve three brain regions that play a part in psychosis. This was done inside an MRI scanner, to monitor brain activity. The results reported that abnormal brain activity was less severe in patients who received cannabidiol compared to those who had a placebo.
Furthermore, the team is planning to launch a large-scale trial into the possible anti-psychotic benefits of cannabidiol. “There is an urgent need for a safe treatment for young people at risk of psychosis,” said Sagnik Bhattacharyya, an author on the study. “One of the main advantages of cannabidiol is that it is safe and seems to be very well tolerated, making it in some ways an ideal treatment. If successful, this trial will provide definitive proof of cannabidiol’s role as an antipsychotic treatment and pave the way for use in the clinic.” The research was published in the journal JAMA Psychiatry in August 2018.